Selected Peer-reviewed Publications (out of 376)

  1. Goessling W, North TE, Loewer S, Lord AM, Sang L, Stoick-Cooper C, Weidinger G, Puder M, Daley GQ, Moon RT, and Zon LI.  Genetic interaction between PGE2 and wnt signaling regulates developmental specification of stem cells and regeneration.  2009, Cell, March 20;136:1136-1146. PMCID: PMC2692708
  2. North TE, Goessling W, Peeters M, Li P, Lord AM, Dzierzak E, and Zon LI.  Hematopoietic stem cell development is dependent on blood flow. Cell, 2009, 137(4):736-748. PMCID: PMC2692708
  3. de Jong JLO, Davidson AJ, Wang Y, Palis J, Opara P, Pugach E, Daley GQ, and Zon LI.  Interaction of retinoic acid and scl controls primitive blood development.  Blood, 2010 Apr 21. PMCID: PMC2910607
  4. Bai X, Kim J, Yang Z, Jurynec M, Lee J, LeBlanc J, Sessa A, Jiang H, Grunwald DJ, Lin S, Orkin SH, Zon LI.  TIF1g controls erythroid cell fate by regulating transcriptional elongation. Cell, 2010 Jul 9;142(1):133-143. PMCID: PMC3072682
  5. de Jong J, Zon LI.  Characterization of immune-matched hematopoietic transplantation in zebrafish.  Blood. 2011. Apr 21;117(16):4234-42. Epub 2011 Feb 23. PMCID: PMC3087475
  6. Mosimann C, Kaufman CK, Li P, Pugach EK, Tamplin OJ, and Zon LI. Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish.  Development, 2010, 138:169-177. 212. PMCID: PMC2998170
  7. Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferre F, Bourque C, Burke C, Turner L, Uong A, Johnson LA, Beroukhim R, Mermel CH, Loda M, Slimane A-S-A, Garraway L, Young RA, and Zon LI.  The SETDB1 histone methyltransferase is recurrently amplified in and accelerates melanoma.  Nature, 2011, Mar 24:471, 513-517. PMCID: PMC3348545
  8. White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahls PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, Granter S, Young RA, Morrison S, Wheeler GN, and Zon LI.  DHODH modulates transcriptional elongation in the neural crest and melanoma.  Nature. 2011, Mar 24:471, 518-522. PMCID:PMC3759979
  9. Trompouki E*, Bowman TV*, Lawton LN, Fan ZP, Wu D-C, DiBiase A, Martin CS, Cech JN, Sessa AK, Leblanc JL, Li P, Durand E, Mosimann C, Heffner GC, Daley GQ, Paulson RF, YoungRA and Zon LI.  Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell, 2011, October 28:147 (3);577-589. PMCID: PMC3219441
  10. Taylor AM, Humphries JM, White RM, Murphey RD, Burns CE, and Zon LI. Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.  Experimental Hematology, 2012 March; 40(3):228-237.e5. PMCID: PMC3310385
  11. Ganis JJ, Hsia N, Trompouki E, de Jong JLO, DiBiase A, Lambert JS, Jia Z, Sabo PJ, Weaver M, Sandstrom R, Stamatoyannopoulos JA, Zhou Y, and Zon LI.  Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Dev Biol, 2012, June 15. Volume 366, Issue 2:185-194. PMCID:PMC3378398
  12. Le X, Pugach EK, Hettmer S, Storer NY, Liu J, Wills A, Dibiase A, Chen EY, Ignatius MS, Poss KD, Wagers AJ, Langenau DM, and Zon LI. A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development. 2013 Apr 24: 140, 2354-2364.
  13. Storer NY, White RM, Uong A, Price E, Nielsen GP, Langenau DM, and Zon LI.  Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis.  Develop 2013:140, 3040-3050.
  14. Albacker CE, Storer NY, Langdon EM, DiBiase A, Zhou Y, Langenau DM, and Zon LI.  The histone methyltransferase SUV39H1 suppresses embryonal rhabdomyosarcoma formation in zebrafish.  PLoS ONE, 2013; 8(5): e64969. PMCID: PMC3660348
  15. Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI. A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. Cell. 2013 Nov
    7;155(4):909-21. PMCID: PMC3902670.
  16. Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nat Cell Biol. 2013
    Dec;15(12):1516-25. PMCID: PMC3959952.
  17. Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagedorn EJ, Li P, Yzaguirre AD, Speck NA, Zon LI. Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche. Cell. 2015 Jan 15;160(1-2):241-52. PMCID:PMC4346256.
  18. Ablain J, Durand EM, Yang S, Zhou Y, Zon LI. A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish. Dev Cell. 2015 Mar 23;32(6):756-64. PMCID: PMC4379706.
  19. Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. 2015 Jul 23;523(7561):468-71. PMID: 26201599.
  20. Mosimann C, Panáková D, Werdich AA, Musso G, Burger A, Lawson KL, Carr LA, Nevis KR, Sabeh MK, Zhou Y, Davidson AJ, DiBiase A, Burns CE, Burns CG, MacRae CA, Zon LI. Chamber identity programs drive early functional partitioning of the heart. Nat Commun. 2015 Aug 26;6:8146. PMCID: PMC4560818.
  21. Kaufman CK, Mosimann C, Fan ZP, Yang S, Thomas AJ, Ablain J, Tan JL, Fogley RD, van Rooijen E, Hagedorn EJ, Ciarlo C, White RM, Matos DA, Puller AC, Santoriello C, Liao EC, Young RA, Zon LI. A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation. Science. 2016 Jan 29;351(6272):aad2197. PMID: 26823433.