Selected Peer-reviewed Publications:

  1. Ablain J, Xu M, Rothschild H, Jordan RC, Mito JK, Daniels BH, Bell CF, Joseph NM, Wu H, Bastian BC, Zon LI, Yeh I. Human tumor genomics and zebrafish modeling identify SPRED1 loss as a driver of mucosal melanoma. Science. 2018 Nov 30.
  2. Mandelbaum J, Shestopalov IA, Henderson RE, Chau NG, Knoechel B, Wick MJ, Zon LI. Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma. J Exp Med. 2018 Sep 12.
  3. Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, Chatrizeh M, Chase ME, Weis O, Zhou Y, Serhan CN, Zon LI. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9252-9257.
  4. Kapp FG, Perlin JR, Hagedorn EJ, Gansner JM, Schwarz DE, O’Connell LA, Johnson NS, Amemiya C, Fisher DE, Wölfle U, Trompouki E, Niemeyer CM, Driever W, Zon LI. Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche. Nature. 2018 Jun;558(7710): 445-448.
  5. Blaser BW, Moore JL, Hagedorn EJ, Li B, Riquelme R, Lichtig A, Yang S, Zhou Y, Tamplin OJ, Binder V, Zon LI. CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. J Exp Med. 2017 Apr 3;214(4):1011-1027.
  6. Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, Pandell N, Avagyan S, Brogie JE, van Rooijen E, Hagedorn EJ, Shyh-Chang N, White RM, Price DH, Pandolfi PP, Peterlin BM, Zhou Y, Kim TH, Asara JM, Chang HY, Young RA, Zon LI. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Mol Cell. 2016 Apr 7;62(1):34-46.
  7. Kaufman CK, Mosimann C, Fan ZP, Yang S, Thomas AJ, Ablain J, Tan JL, Fogley RD, van Rooijen E, Hagedorn EJ, Ciarlo C, White RM, Matos DA, Puller AC, Santoriello C, Liao EC, Young RA, Zon LI. A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation. Science. 2016 Jan 29;351(6272):aad2197.
  8. Mosimann C, Panáková D, Werdich AA, Musso G, Burger A, Lawson KL, Carr LA, Nevis KR, Sabeh MK, Zhou Y, Davidson AJ, DiBiase A, Burns CE, Burns CG, MacRae CA, Zon LI. Chamber identity programs drive early functional partitioning of the heart. Nat Commun. 2015 Aug 26;6:8146.
  9. Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. 2015 Jul 23;523(7561):468-71.
  10. Ablain J, Durand EM, Yang S, Zhou Y, Zon LI. A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish. Dev Cell. 2015 Mar 23;32(6):756-64.
  11. Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagedorn EJ, Li P, Yzaguirre AD, Speck NA, Zon LI. Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche. Cell. 2015 Jan 15;160(1-2):241-52.
  12. Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nat Cell Biol. 2013
    Dec;15(12):1516-25.
  13. Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI. A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. Cell. 2013 Nov 7;155(4):909-21.
  14. Albacker CE, Storer NY, Langdon EM, DiBiase A, Zhou Y, Langenau DM, and Zon LI.  The histone methyltransferase SUV39H1 suppresses embryonal rhabdomyosarcoma formation in zebrafish.  PLoS ONE, 2013; 8(5): e64969.
  15. Storer NY, White RM, Uong A, Price E, Nielsen GP, Langenau DM, and Zon LI.  Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis.  Develop 2013:140, 3040-3050.
  16. Le X, Pugach EK, Hettmer S, Storer NY, Liu J, Wills A, Dibiase A, Chen EY, Ignatius MS, Poss KD, Wagers AJ, Langenau DM, and Zon LI. A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development. 2013 Apr 24: 140, 2354-2364.
  17. Ganis JJ, Hsia N, Trompouki E, de Jong JLO, DiBiase A, Lambert JS, Jia Z, Sabo PJ, Weaver M, Sandstrom R, Stamatoyannopoulos JA, Zhou Y, and Zon LI.  Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Dev Biol, 2012, June 15. Volume 366, Issue 2:185-194.
  18. Taylor AM, Humphries JM, White RM, Murphey RD, Burns CE, and Zon LI. Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.  Experimental Hematology, 2012 March; 40(3):228-237.e5.
  19. Trompouki E*, Bowman TV*, Lawton LN, Fan ZP, Wu D-C, DiBiase A, Martin CS, Cech JN, Sessa AK, Leblanc JL, Li P, Durand E, Mosimann C, Heffner GC, Daley GQ, Paulson RF, YoungRA and Zon LI.  Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell, 2011, October 28:147 (3);577-589.
  20. White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahls PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, Granter S, Young RA, Morrison S, Wheeler GN, and Zon LI.  DHODH modulates transcriptional elongation in the neural crest and melanoma.  Nature. 2011, Mar 24:471, 518-522.
  21. Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferre F, Bourque C, Burke C, Turner L, Uong A, Johnson LA, Beroukhim R, Mermel CH, Loda M, Slimane A-S-A, Garraway L, Young RA, and Zon LI.  The SETDB1 histone methyltransferase is recurrently amplified in and accelerates melanoma.  Nature, 2011, Mar 24:471, 513-517.
  22. Mosimann C, Kaufman CK, Li P, Pugach EK, Tamplin OJ, and Zon LI. Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish.  Development, 2010, 138:169-177. 212.
  23. de Jong J, Zon LI.  Characterization of immune-matched hematopoietic transplantation in zebrafish.  Blood. 2011. Apr 21;117(16):4234-42.
  24. Bai X, Kim J, Yang Z, Jurynec M, Lee J, LeBlanc J, Sessa A, Jiang H, Grunwald DJ, Lin S, Orkin SH, Zon LI.  TIF1g controls erythroid cell fate by regulating transcriptional elongation. Cell, 2010 Jul 9;142(1):133-143.
  25. de Jong JLO, Davidson AJ, Wang Y, Palis J, Opara P, Pugach E, Daley GQ, and Zon LI.  Interaction of retinoic acid and scl controls primitive blood development.  Blood, 2010 Apr 21.
  26. North TE, Goessling W, Peeters M, Li P, Lord AM, Dzierzak E, and Zon LI.  Hematopoietic stem cell development is dependent on blood flow. Cell, 2009, 137(4):736-748.
  27. Goessling W, North TE, Loewer S, Lord AM, Sang L, Stoick-Cooper C, Weidinger G, Puder M, Daley GQ, Moon RT, and Zon LI.  Genetic interaction between PGE2 and wnt signaling regulates developmental specification of stem cells and regeneration.  2009, Cell, March 20;136:1136-1146.

For more a more updated and complete list, please see https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40439065/?sort=date&direction=descending